| Desmodium intortum (Mill.) Urb., 1920 |
| Desmodium jaliscanum S. Watson, 1887 |
| Desmodium jaliscanum var. obtusum B.L. Rob., 1891 |
| Desmodium johnstonii Standl. ex B.G. Schub., 1941 |
| Desmodium karwinskii (Schindl.) L. Torres & A. Delgado, 2020 |
| Desmodium lamprocarpum Hemsl., 1879 |
| Desmodium langlasseanum (Schindl.) Standl., 1936 |
| Desmodium lavanduliflorum Standl., 1937 |
| Desmodium lempirae C. Nelson, 1996 |
| Desmodium leptoclados Hemsl., 1880 |
| Desmodium leptomeres (Blake) B.G. Schub. & McVaugh, 1924 |
| Desmodium lilloanum (Schindl.) Burkart, 1939 |
| Desmodium lindheimeri Vail, 1891 |
| Desmodium lineatum (Michx.) DC., 1825 |
| Desmodium lupulinum Schltdl., 1838 |
| Desmodium luteocanescens M.E. Jones, 1929 |
| Desmodium luteolum Standl., 1938 |
| Desmodium macrodesmum (S.F. Blake) Standl. & Steyerm., 1946 |
| Desmodium macropodium Hemsl., 1880 |
| Desmodium macrostachyum Hemsl., 1880 |