| Comastes Osten-Sacken, 1877 |
| Conophorini Becker, 1913 |
| Conophorus Meigen, 1803 |
| Conophorus atratulus (Loew, 1872) |
| Conophorus fenestratus (Osten-Sacken, 1877) |
| Coptopelma Enderlein, 1926 |
| Corycetta Hull, 1973 |
| Crocidiinae Hull, 1973 |
| Cyananthrax Painter, R. H., 1959 |
| Cyananthrax cyanopterus (Wiedemann, 1830) |
| Cyclorhynchus Macquart, 1840 |
| Cyclorrhynchus Bezzi, 1924 |
| Cythereinae Becker, 1913 |
| Dagestania Paramonov, 1929 |
| Defilippia Lioy, 1864 |
| Desmatomyia Williston, 1895 |
| Desmatomyia anomala Williston, 1895 |
| Desmatomyia binotata Painter, R. H., 1968 |
| Desmatomyia jambalaia Hall & Evenhuis, 1987 |
| Desmatomyiinae Hall & Evenhuis, 1987 |