| Parasicyos dieterleae Lira & R. Torres, 1991 |
| Parasicyos maculatus Dieterle, 1975 |
| Pepo Mill., 1754 |
| Pepo ficifolius (Bouché) Britton, 1925 |
| Pepo foetidissima (Kunth) Britton, 1913 |
| Pepo malabaricus Sageret, 1826 |
| Pepo okeechobeensis Small, 1930 |
| Peponopsis Naudin, 1860 |
| Peponopsis adhaerens Naudin, 1860 |
| Pileocalyx Gasp., 1847 |
| Pittiera Cogn., 1891 |
| Pittiera grandiflora (Cogn.) Cogn. ex Rose, 1897 |
| Pittiera longipedunculata Cogn., 1891 |
| Pittiera parvifolia Cogn. & Rose, 1897 |
| Pittiera trilobata Cogn., 1895 |
| Polakowskia Pittier, 1910 |
| Polyclathra Bertol., 1840 |
| Polyclathra albiflora (Cogn.) C. Jeffrey, 1971 |
| Polyclathra cucumerina Bertol., 1840 |
| Polyclathra grandiflora (Cogn.) C. Jeffrey, 1971 |