| Sphaerosyllis Claparède, 1863 |
| Sphaerosyllis glandulata Perkins, 1981 |
| Sphaerosyllis hystrix Pettibone, 1963 |
| Sphaerosyllis longicirrata Webster & Benedict, 1884 |
| Sphaerosyllis magnidentata Perkins, 1981 |
| Sphaerosyllis pirifera Claparède, 1868 |
| Sphaerosyllis piriferopsis Perkins, 1981 |
| Sphaerosyllis riseri Perkins, 1981 |
| Sphaerosyllis taylori Perkins, 1981 |
| Sphaerosyllis tetralobata Salcedo-Oropeza, San Martín & Solís-Weiss, 2016 |
| Streptospinigera Kudenov, 1983 |
| Streptosyllis Webster & Benedict, 1884 |
| Streptosyllis pettiboneae Perkins, 1981 |
| Syllidae Grube, 1850 |
| Syllides Örsted, 1845 |
| Syllides bansei Perkins, 1981 |
| Syllides caribica Licher, 1996 |
| Syllides fulvus (Marion & Bobretzky, 1875) |
| Sylline Grube, 1860 |
| Syllis Lamarck, 1818 |