| Piper bisasperatum Trel., 1929 |
| Piper biseriatum C. DC., 1920 |
| Piper blandum Jacq., 1791 |
| Piper botterii C. DC., 1920 |
| Piper bourgeaui C. DC., 1872 |
| Piper brachypus Trel., 1921 |
| Piper bredemeyeri J. Jacq., 1816 |
| Piper breedlovei Callejas, 2020 |
| Piper brevipedicellatum Bornst., 1989 |
| Piper bryogetum C. DC., 1920 |
| Piper buchingeri C. DC. ex Callejas, 2020 |
| Piper caladiifolium (Miq.) C. DC., 1869 |
| Piper calcariformis Tebbs, 1987 |
| Piper calderonii Trel. ex Callejas, 2020 |
| Piper capacibracteum Trel., 1929 |
| Piper carpinteranum C. DC., 1897 |
| Piper carrilloanum C. DC., 1891 |
| Piper ceanothifolium Kunth, 1815 |
| Piper cenocladum C. DC., 1897 |
| Piper chamissonis (Miq.) Steud. ex C. DC., 1869 |