| Piper disjunctum C. DC., 1872 |
| Piper distachyon L., 1753 |
| Piper divaricatum G. Mey., 1818 |
| Piper dolichotrichum Yunck., 1952 |
| Piper donnell-smithii C. DC., 1894 |
| Piper dotanum Trel., 1929 |
| Piper dryadum C. DC., 1892 |
| Piper emarginellum Sw. ex Wikstr., 1828 |
| Piper epigynium C. DC., 1872 |
| Piper eriopodon (Miq.) C. DC., 1869 |
| Piper fallens Trel., 1929 |
| Piper fasciculatum Ruiz & Pav., 1798 |
| Piper fenianum Trel., 1926 |
| Piper fimbrirachium Callejas, 2020 |
| Piper fimbriulatum C. DC., 1892 |
| Piper fischerianum C. DC., 1869 |
| Piper flavidum C. DC., 1894 |
| Piper flavirameum C. DC., 1920 |
| Piper fortunaense Tebbs, 1990 |
| Piper fortunyoanum Trel., 1940 |